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Obesity, alcohol abuse, cigarette smoking, and heavy metals have been firmly linked with OS

15 As a transcription factor, c-Myc directly binds to DNA at E-box domains (CACGTG or similar sequences) as a heterodimer with one of its bHLHLZ interacting partners, Max being the most common

Zacharias HD, Kamel F, Tan J, et al
This change in genetic transcription results in changes inside of the cell including the production of proteins and enzymes which then impact how that cell functions
