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Biochimie 94, 588596

Its core is the autophagy-related gene (ATG)-regulated lysosomal degradation pathway, which degrades and recycles damaged organelles or proteins by forming autophagolysosomes to cope with stress and maintain homeostasis ( In Vitro studies have revealed a new role for autophagy in cancer cell death, indicating that autophagy can trigger ferroptosis by initiating ferritin decomposition ( 5 Ferroptosis and the core pathology of AD 5.1 Ferroptosis and A plaques A misfolding and aggregation are key to AD pathology, with iron dysregulation promoting ferroptosis ( + , reducing it to Fe + and accelerating plaque formation via iron-mediated oxidation ( A bidirectional regulatory network exists between A deposition and ferroptosis

Dietary zinc deficiency enhances esophageal cell proliferation and N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumor incidence in C57BL/6 mouse

The follow-up period varied widely between 6 and 12 months after injection making it hard to know when and how recovery occurred