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Materials and methods Animals and SS-31 treatment Young (3-month-old) and aged (24-month-old) male C57BL/6 inbred mice (Jackson Laboratories) were used in this study

Discussion The chromatin structure of telomeres is regulated by methylation of H3K9 and H4K20, labeled as heterochromatin, and acetylation of histones H3 and H4, labeled as euchromatin 16

VEGF, MMP, glutamate, and other substances are specific promoters of BBB integrity loss and are associated with astrocyte activation following TBI (128, 129)

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It can indicate peptide aggregation (clumping of denatured peptide molecules), bacterial contamination, or incompatible diluent