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A later study found that RSV infection down-regulates NRF2 expression in airway epithelial cells and a decrease in the expression of airway antioxidant enzymes led to additional oxidative stress

ROS stimulates the extrinsic apoptotic pathway by promoting the ubiquitin degradation of the cellular FADDlike IL1converting enzymeinhibitory protein (cFLIP), which inhibits the formation of deathinducing signaling complex (DISC) via competitively combining with FADD [150]

& Miesenbck, G

Controlling the false discovery rate: a practical and powerful approach to multiple testing

[DOI] [PubMed] [Google Scholar] 5.Hodgman MJ, Garrard AR