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Data from different clinical trials show an average reduction of 1.4%-2% in HbA1c level and an 8-10% in body weight after 30-56 weeks of treatment

However, due to the progressive nature of diabetes, a second-line medication is commonly required at some point in the course of the disease to maintain glucose homeostasis

An orally active allosteric GLP-1 receptor agonist is neuroprotective in cellular and rodent models of stroke

The parabrachial nucleus: CGRP neurons function as a general alarm

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