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Description
GPX4 requires GSH, a strong reducing agent, as a cofactor to effectively reduce phospholipid hydroperoxides (PLOOHs) to their equivalent alcohols (PLOHs) inside cells
Cells 12, 1012
Of note, LY341495 treatment decreases the stimulation of the MAPK pathway [74], suggesting that the mGlu2/3-MAPK axis serves to support the proliferation of glioblastoma cells
[DOI] [PubMed] [Google Scholar] McGuinness AJ, Sapey E
This timing prevents confusion about which compound is causing any side effects you might experience
