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These DAMPs stimulate Pattern Recognition Receptors (PRRs) and the NLRP3 inflammasome, promoting persistent neuroinflammation ( Crucially, neuronal homeostasis relies on the structural and functional tethering of the endoplasmic reticulum (ER) and mitochondria via Mitochondria-Associated Membranes (MAMs)

The fingerprints are not disease specific, but healthy and diseased fingerprints are remarkably different

doi: 10.1002/rmv.454

Biomaterials 35:85768584 [DOI] [PubMed] [Google Scholar] Lam LK, Pai RP, Wattenberg LW (1979) Synthesis and chemical carcinogen inhibitory activity of 2-tert-butyl-4-hydroxyanisole

J Stem Cells