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Taken together, these findings suggest that APR-246 could induce tumor cell death through both reactivation of mutant p53 and inhibition of cellular thiol-dependent redox system proteins (GPX4, TXNDR1, GRX1), providing novel combinatorial strategies for AML therapy

Journal of Aging Research & Clinical Practice

[,] TCM has a variety of antitumor effects in treating liver cancer and can play a greater role in other treatments

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