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Description
It's not a shortcut

Since the HSP90-CDC37 complex stabilizes several kinases (53), these observations suggest that CDK4/6-inhibitors, by disrupting the interaction between CDC37 and CDK4 or CDK6, might promote degradation of these CDKs
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Glutathione, one of the most abundant cellular metabolites, maintains cellular environment in reduced state, protecting proteins and iron-sulfur clusters from oxidative stress and is essential for biosynthesis reactions, such as nucleotide synthesis 3

The Z-score column corresponds to the SDR Z-score computed using mean and standard deviation values from a Guassian fit