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Use with NSAIDs, aspirin, warfarin, or other drugs that affect coagulation may potentiate the risk of gastrointestinal or other bleeding (5.7) Angle-Closure Glaucoma: Angle-closure glaucoma has occurred in patients with untreated anatomically narrow angles treated with antidepressants (5.8) Hyponatremia: Has been reported with PROZAC in association with syndrome of inappropriate antidiuretic hormone (SIADH)

An empty stomach can raise peak blood alcohol content by 2550% compared to drinking after a substantial meal

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While preliminary data suggest potential interactions with cellular repair mechanisms, further studies are required