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I dont think pharma is necessarily incentivized to figure out the dosing in this population thats looking to use less medicine. Rybelsus, an Food and Drug Administration-approved oral GLP-1 drug, is approved to treat Type 2 diabetes but not weight loss

Consistent with these findings, the BWMR analysis in the validation cohort (FinnGen Consortium) showed suggestive evidence of a protective effect of elevated GLP-1R gene expression against DR risk (OR = 0.70, 95% CI: 0.510.96, P = 0.029)

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Cao Y, Hlscher C, Hu M-M, Wang T, Zhao F, Bai Y, et al

The pathogenetic reasons underlying this interplay are not yet fully understood, but various hypotheses have been formulated
