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Description
Comprehensive Physiology
Cell 71(3):398408 [DOI] [PubMed] [Google Scholar] 28.Murphy MP
Tanmahasamut, P
also argued that c-MET mutation, c-MET amplification, or total c-MET expression, but not phospho-MET expression, have been used as markers for patient selection in these trials, which led to the inclusion of a large proportion of patients who will not benefit from the c-MET inhibitor, resulting in trial failure
In particular, lower levels of adiponectin and increased expression of TNF- and its soluble receptor have been recently related to the development of NASH (43)
