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Non-linear effects were observed in the placebo group, driven by higher MACE incidence among participants with at least 5% weight loss, consistent with possible unintentional or illness-related weight loss
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Tirzepatide (Mounjaro/Zepbound) activates GLP-1 and GIP receptors
"What we do know is GLP-1s impact the reward centre in the brain, which is why you're having less food noise, fewer cravings and less interest in alcohol use
10.1038/s42003-023-04627-2 51 FuruyamaK.CheraS.Van GurpL.OropezaD.GhilaL.DamondN.et al (2019)
