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+ - NNMT inhibitors are emerging as a promising area of research with potential therapeutic applications across a range of diseases

For the reasons presented in the sections above, this approach would exclude a significant fraction of patients for which serum vitamin B 12 does not reflect cellular, genetic, and pharmacological disturbances that lead to functional vitamin B 12 deficiency

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If they make an exception for one patient, they may feel pressured to do so for others, leading to a system where ad-hoc changes become the norm

But do B12 injections actually promote weight loss