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Description
This enzyme is important in glutathione metabolism, since, by breaking the gamma-glutamyl moiety of GSH, GSSG or GSH conjugates, the free glutamate is rapidly transferred to another external amino acid that originates a gamma-glutamyl-amino acid and the dipeptide cysteine-glycine [49]
Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy
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: . (Glutathione) Tripeptide Cysteine , Glycine , Glutamic acid 1
The copper ion binds to the peptide through a square-planar pyramid configuration, creating an extraordinarily stable complex with a binding affinity (pK = 16.44) approximately 10 million times higher than other tripeptides
