semaglutide sketchy Why I think Henry meds is : r/henrymeds Insulin & diabetes for pharmacology
Description
The pathological mechanism might be the dysregulation of glucose metabolism, which triggered the accumulation of epicardial adipose tissue (EAT) and free fatty acids in heart, leading to myocardial lipotoxicity, oxidative stress, and mitochondrial dysfunction [41]
Ozempic microdosing refers to using smaller doses, typically starting at 0.05 mg, which is lower than the standard therapeutic dose (0.25 mg)
Patients with genetic variants suggesting lower GLP-1 responsiveness may benefit from dual-compound strategies, while those with strong receptor sensitivity often succeed with semaglutide alone
The pathophysiology of DICLE is not fully understood but is thought to involve genetic, epigenetic, and pharmacokinetic involvement [4]
Q: Have GLP-1s affected the MUSC Weight Management Centers approach
