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Leyris, J

Superoxide anion chemistry-its role at the core of the innate immunity

The Balk group has focussed on the mitochondrial and cytosolic assembly pathways in plants: Fe-S cluster assembly proteins in mitochondria ATM3, an ABC transporter involved in glutathione export from mitochondria Fe-S cluster assembly in the cytosol Fe-S cluster assembly proteins in mitochondria The ~12 proteins associated with the mitochondrial ISC pathway are divided in the core assembly machinery and downstream carrier proteins

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Silencing this gene can decrease Bcl-2 expression and increase Bax protein expression, leading to a reduced Bcl-2/Bax ratio, thereby promoting prostate cell apoptosis [38]