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doi: 10.1038/s41598-023-32974-x 278 OkadaMKimHWMatsu-UraKWangYGXuMAshrafM

Altered mitochondrial function leads to a reduction in energy production and an increase in reactive oxygen species, which negatively impacts all cellular functions such as calcium handling, anaplerosis, proteostasis, apoptosis, and autophagy [27,28,29]

[3] Malaguarnera M, Cauli O

Gastroenterology Hepatology 29, 867878

Loss of Ozz or Alix in mouse skeletal muscle reciprocally influences each others roles as mitochondrial QC systems: Ozz deficiency increases the pool of exosome-loaded Slc25A4, while Alix deficiency redirects Slc25A4 to proteasomal degradation