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Calorie Restriction with or without Time-Restricted Eating in Weight Loss (Liu et al.) New England Journal of Medicine 2022 12-month RCT (n=139) supporting the claim that when total calories are matched, time-restricted eating is 'not dramatically better' than daily calorie restriction for weight, body fat, or metabolic risk
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However, a significant induction of Glp1r and Ppar mRNA transcripts was detected in metformin-treated INS-1 832/3 cells at both glucose concentrations (Fig
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