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FDA Clarifies Policies for Compounders as National GLP-1 Supply Begins to Stabilize

Although both medications belong to the GLP-1 category, they are not identical

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In clinical trials, retatrutide achieved 24.2% weight loss at 48 weeks versus tirzepatide approximately 21% at 72 weeks, suggesting stronger overall appetite and metabolic effects

This limitation reflects the broader issue of inconsistent reporting of sex-disaggregated outcomes in diabetes-treatment research and underscores the need for future research to systematically explore and report the effects of diabetes treatments according to sex
