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By utilizing the glucagon pathway alongside GLP-1, mazdutide alters hepatic glucose output while simultaneously upgrading peripheral insulin sensitivity through weight loss
Discontinuation of GLP1RAs and tirzepatide can also result in a loss of the beneficial anti-atherosclerotic and plaque-stabilizing effects of these medications

[DOI] [PubMed] [Google Scholar] 63.Fan W., Yanase T., Morinaga H., Okabe T., Nomura M., Daitoku H., Fukamizu A., Kato S., Takayanagi R., Nawata H
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[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Suzuki Y
