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We hypothesize that this resulted from a combination of medications targeting multiple eating behavior pathways simultaneously, including appetite, satiety, food craving, and binge-eating tendencies (see Table 1)

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Experts recommend formulators focus on toning down the flavors and building formulas through sensory design to complement slower eating habits

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5961 Bone fractures The US FDA added a warning in September 2015 about reductions in bone density and increased risk for bone fractures with the use of canagliflozin in patients with T2DM

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