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This informal use preceded Wegovy's formal FDA approval in November 2021, though prescribing off-label carried no official weight-loss indication and often faced insurance denials

Compounders sue FDA over removal of semaglutide from official shortage list Drug compounders have sued the FDA to put the weight loss and diabetes drug semaglutide back on an official shortage list, fighting a regulatory decision Sign up to read this article for free

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Demand for GLP-1 improves the capacity utilisation of fill-finish capabilities offered by CDMOs While GLP-1 manufacturers are investing significantly in the development of the drug, few have the capacity to complete filling and packaging in-house