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Variations in the GLP1R gene (rs6923761) and GIPR gene (rs1800437) determine how sensitive your appetite-control centers are to the medication

A study on semaglutide (Ozempic, Wegovy) found that up to 39% of weight lost came from muscle mass , not fat

Expanded Therapeutic Applications of GLP-1 Medications 1

Glucagon-like peptide-1 (GLP-1) is a naturally occurring hormone your intestines release after eating, signaling fullness to your brain and slowing stomach emptying

Additionally, cardiovascular and metabolic benefits observed at therapeutic doses might be partially retained at lower doses, though this remains speculative without dedicated dose-finding studies