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In the human body, the PLG polymers slowly degrade through the non-catalyzed hydrolysis of the ester linkages into lactic acid and glycolic acid, which are finally eliminated as carbon dioxide and water

[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Rinella M.E., Neuschwander-Tetri B.A., Siddiqui M.S., Abdelmalek M.F., Caldwell S., Barb D., Kleiner D.E., Loomba R

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Logistic regression models estimated odds ratios (ORs) for analysis

Conclusion GLP-1 RAs provide clinically meaningful weight loss primarily through selective fat mass reduction, with relative preservation of lean tissue, supporting their role in achieving quality weight loss