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While Semaglutide GLP-1 is generally considered safe and effective for most individuals with obesity, there are certain groups of people who may not be able to use Semaglutide GLP-1 due to potential risks and contraindications

They may

Nevertheless, understanding GI adverse events across both earlier and newer GLP-1based therapies remains highly relevant, particularly as these agents are increasingly prescribed for long-term and off-label indications

This has increased interest in pharmacological treatment options

Guided self-help based on CBT principles : For those with less severe presentations, structured self-help programmes with support from a healthcare professional can be effective and are more readily accessible