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In severe cases, this may lead to a more serious condition known as gastroparesis or paralysis of the stomach

Similarly, the association for OCD was significant in the PGC dataset (OR = 2.30, 95% CI [1.26, 4.22]) but not in FinnGen

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Referral to a dermatologist may be considered if you have severe nodulocystic acne, acne at risk of permanent scarring, acne that has not responded to adequate courses of standard treatments, or acne causing significant psychological distress