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Safety Considerations and Dose Adjustments Semaglutide at any dose requires baseline kidney function assessment and periodic monitoring, especially as doses increase toward 2.4 mg or higher

Kidney and liver disease, in some cases

From what I've gathered through my own research and talking to others, Ozempic (and similar medications like those containing tirzepatide) works by slowing down gastric emptying

Fewer Steps and Less Exercise The results showed a clear decline in movement after treatment began

This motion contracts the muscle in the calf of the leg and can cause a severe cramp or charley horse
