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The metabolic rate of GLP-1R KO mice was significantly slower than that of WT mice (p=0.0345, WT mice 0.023350.057mM/min, GLP-1R KO mice 0.019980.07mM/min)

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Type 2 diabetes mellitus (T2DM) is closely linked to oxidative stressinduced mitochondrial dysfunction, disrupting the balance between fusion and fission processes and driving hepatic injury

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