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Mice then received five consecutive daily intraperitoneal tamoxifen injections and were anesthetized with 3% isoflurane for subcutaneous implantation of an osmotic pump (Alzet 1002) delivering either PBS or 1.2 nmol/day RF-409
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A tight jaw generates tension extending to the neck, shoulder, and upper back muscles

Abrupt reduction in body mass can affect one's bodily mechanics as well as heighten the possibility of experiencing back pain
