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Discuss key efficacy and tolerability data from clinical trials published to date with oral semaglutide

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Its physiological actions include stimulating glucose-dependent insulin secretion from pancreatic beta cells, suppressing glucagon release, slowing gastric emptying, and promoting satiety through central nervous system pathways

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In primary human hepatocytes, GLP-1 RAs reduced lipogenesis by approximately 24.6% compared to untreated controls
