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Materials and methods: We performed high-throughput screening of a compound library in MIN6 cells expressing pHluorin-LC3-mCherry reporter, with which pHluorin/mCherry fluorescence ratio decreases in response to an increase in autophagic flux, to determine agents upregulating the autophagic flux

Beyond GLP-1, newer medications are incorporating glucose-dependent insulinotropic polypeptide (GIP) and glucagon pathways
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Custom antibodies could be raised against retatrutide for ELISA-style detection

R., Brown, M
