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When combined with semaglutide, which produces robust appetite suppression and significant weight loss for most patients, fluoxetines effect on appetite is relatively minor in comparison

If you take semaglutide with insulin or an insulin secretagogue (eg, a sulfonylurea), blood glucose should be monitored, and a dose reduction in the insulin or the sulfonylurea may be necessary to avoid hypoglycemia
On Day 61 or thereafter, if: (2.2) o No additional glycemic control is needed, maintain the dosage at 7 mg orally once daily
