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I have found the ZOE podcast interesting (no financial involvement) And Margaret MCartnetny view in the BMJ see also Weight Loss in Lactation | InfantRisk Center July 2025 please be aware of the risk of pancreatitis GLP-1 receptor agonists: MHRA to study possible side effects after acute pancreatitis cases | The BMJThe BMJ Data from the Medicines and Healthcare Products Regulatory Agency (MHRA) show that hundreds of cases of acute and chronic pancreatitis, including 10 deaths, have been reported in people taking the drugs, which are used to treat weight loss and diabetes by mimicking a natural hormone released after eating, although it is not certain that the drugs are the cause. June 2025 the MHRA recommended that all women taking skinny jabs should use effective contraception

Thomas MK, Nikooienejad A, Bray R et al (2021) Dual GIP and GLP-1 receptor agonist tirzepatide improves beta-cell function and insulin sensitivity in type 2 diabetes

While neither is commercially available as a prescription drug yet, research-grade peptide costs differ between the two

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For instance, the classic version of the ketogenic diet (in use since 1921 for epilepsy) contains even more fat and less carbohydrate and protein [8,9]
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