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doi:10.1002/jcph.1765 168
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In SURMOUNT-1, tirzepatide reached 20.9% mean weight loss at 72 weeks on the highest-dose arm (n=2,539)
The delayed gastric emptying caused by GLP-1 agonists might theoretically contribute to reduced alcohol consumption by altering absorption kinetics and the subjective experience of intoxication, though this hypothesis requires human pharmacokinetic studies for validation
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